Technologies

AlivaMab® Mouse

Twelve of the top 25 pharma companies use Ablexis’ AlivaMab Mouse, the only transgenic animal with a differentiated design for diversity, speed, developability, and FTO.

To learn more about AlivaMab Mouse, visit www.ablexis.com.

alivamab-mouse-graphic-largeAlivaMab Mouse Design Accelerates Progress from Discovery to Development

Innovative Design

  • Peer-reviewed design for successful antibody discovery and FTO

Track Record

  • Over 500 discovery projects since 2015

Outperformance

  • Superior in direct testing versus in vitro display and other transgenic platforms

Versatility

  • Hybrid, single B cell (plasma and memory), immune repertoire display
  • Standard antibody, bispecifics, ADSs, CARs, etc.

Clinical Validation

  • Multiple AlivaMab antibodies have entered clinical development since 2018

AMMPD Immunizations

Our powerful AMMPD immunization methodologies—which include innovative protein, cell, and DNA immunizations plus protocols that break immune tolerance—elicit very fast, robust, and diverse immune responses to even the most challenging targets in as little as two to six weeks.

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AMMPD immunizations are used alone, in combination, and/or with tolerance-breaking strategies

Function-First Screening

Our high-throughput screening of both plasma and memory IgG+ B cell repertoires interrogates up to hundreds of thousands of hybridomas, which is an order of magnitude greater than some single B cell screening technologies and other hybridoma processes.


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Bispecific Formats

We deliver bispecific antibodies that are designed for valency, affinity, and geometry to drive optimal activity. Further, they are stability engineered and tested for developability to ensure drug-like properties.

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